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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
19.7
Human Site:
S474
Identified Species:
30.95
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S474
N
P
L
G
N
R
A
S
H
S
A
N
S
Q
P
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S474
N
P
L
G
N
R
A
S
H
S
A
N
S
Q
P
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
A226
G
S
R
S
Q
V
F
A
G
D
S
P
P
Q
S
Dog
Lupus familis
XP_534537
1097
121903
V461
I
L
H
P
V
K
S
V
R
V
M
R
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S473
N
P
L
G
S
R
A
S
H
S
A
N
S
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S465
N
P
L
G
N
R
A
S
H
P
A
S
S
Q
P
Chicken
Gallus gallus
XP_419666
1136
127431
S480
N
H
H
G
N
R
Q
S
H
T
S
S
S
Q
P
Frog
Xenopus laevis
NP_001087838
1118
125984
S469
V
A
S
W
Q
V
L
S
N
N
A
Q
T
S
A
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
P460
T
A
V
A
P
A
H
P
P
W
L
Q
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
Y463
N
C
L
E
P
P
S
Y
A
K
S
M
Q
A
K
Honey Bee
Apis mellifera
XP_395146
1137
124999
M510
P
P
S
Y
A
T
T
M
Q
A
L
A
A
Q
R
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
L550
R
I
D
P
N
N
D
L
T
G
G
S
K
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
R173
F
H
Q
P
Q
T
L
R
S
N
G
S
Y
S
S
Red Bread Mold
Neurospora crassa
P38679
598
67999
D15
H
L
N
L
G
T
N
D
T
R
M
A
P
N
D
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
N.A.
N.A.
86.6
60
13.3
6.6
N.A.
13.3
13.3
0
13.3
P-Site Similarity:
100
100
20
26.6
N.A.
100
N.A.
N.A.
93.3
80
33.3
13.3
N.A.
26.6
26.6
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
7
7
27
7
7
7
34
14
7
7
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
7
0
7
0
0
0
0
7
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
34
7
0
0
0
7
7
14
0
0
0
0
% G
% His:
7
14
14
0
0
0
7
0
34
0
0
0
0
0
0
% H
% Ile:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
7
0
0
7
0
7
% K
% Leu:
0
14
34
7
0
0
14
7
0
0
14
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
14
7
0
0
0
% M
% Asn:
40
0
7
0
34
7
7
0
7
14
0
20
0
7
0
% N
% Pro:
7
34
0
20
14
7
0
7
7
7
0
7
27
14
54
% P
% Gln:
0
0
7
0
20
0
7
0
7
0
0
14
7
47
0
% Q
% Arg:
7
0
7
0
0
34
0
7
7
7
0
7
0
0
7
% R
% Ser:
0
7
14
7
7
0
14
40
7
20
20
27
34
14
14
% S
% Thr:
7
0
0
0
0
20
7
0
14
7
0
0
7
0
0
% T
% Val:
7
0
7
0
7
14
0
7
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _